ANXA5 and keloid: MTS assay (Fig. 3b,f) and Annexin V apoptosis detection (Fig. 3c,g) demonstrated that the proliferation and apoptosis of the miR-21-5p inhibitor transfected keratinocytes in both keloid and normal skin groups did not show significant changes compared with the cells transfected with the negative controls (P > 0.05).