Homozygous genotypes for PNPLA3: CC and GG, were more prevalent in NAFLD patients without pericellular fibrosis (61.8 vs 40 % for CC, p = 0.0008 and 13.2 vs 5.3 %, p = 0.04). The gene discussed is PNPLA3; the disease is metabolic dysfunction-associated steatotic liver disease.