ESR1 and neoplasm: For patients treated with radiotherapy or not, there were no significant associations between SNCG expression and Age (p = 0.767, 0.665), Tumor size (p = 0.145, 0.142), Metastasis lymph node (p = 0.117, 0.332), TNM stage (p = 0.428, 0.957), ER status (p = 0.304, 0.998), PR status (p = 0.171, 0.904), or HER2 status (p = 0.351, 0.646), and all of the clinicopathologic features in both subgroups were equally distributed (Table 1).