In accordance with the approach of drug and gene co-delivery via cationic liposomes, nanoscale designed liposomes were used to deliver doxorubicin and TRAIL to produce synergistic apoptotic effct in non-small cell lung cancer (NSLC) [117] and glioblastoma multiforme (GBM) cancer cells [118]. Here, TNFSF10 is linked to glioblastoma.