Mutations in valosin-containing protein (VCP) gene are known to cause an inherited form of IBM with Paget disease and frontotemporal dementia (IBMPFD) (Gidaro et al., 2008, Watts et al., 2004) and have also been reported in cases with ALS and FTD (Johnson et al., 2010, Koppers et al., 2012). The gene discussed is VCP; the disease is inclusion body myopathy with Paget disease of bone and frontotemporal dementia.