Among them, the SQSTM1 p.P392L is also known to be the most frequent SQSTM1 mutation in PDB (Laurin et al., 2002) and has also been reported in cases with FTD (Le Ber et al., 2013) and normal tension glaucoma (Scheetz et al., 2016), whereas VCP p.I27V and p.R159C have also been found in patients with IBMPFD (Chan et al., 2012, Rohrer et al., 2011), and the VCP p.I27V has also been recently reported in one sIBM patient (Weihl et al., 2015). This evidence concerns the gene VCP and frontotemporal dementia.