HMGB2 and neoplasm: Cell surface NR serves as a target for endostatin6 and various carcinogenic ligands.5, 8, 12 The tumor‐homing peptide F3 (KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK) is a 31 amino acid synthetic fragment of the human high mobility group protein 2 (HMGN2).13 F3 was discovered using phage display libraries while searching for proteins capable of homing to the tumor and its vasculature, and it has since been used as a payload carrier to deliver biologically active molecules to tumors.