Cancer cells are protected from excessive damage by reactive oxygen species (ROS) through the simultaneous upregulation of innate protective antioxidant pathways via mechanisms such as nuclear factor, erythroid 2 like 2 (NFE2L2) stabilization (also known as NRF2) and generation of reduced glutathione (GSH) [7, 8]. The gene discussed is NFE2L2; the disease is cancer.