MYC and neoplasm: In comparison to other oncogenes, MYC is unique in the way that it simultaneously influences all cellular pathways that cumulatively contribute to overactive tumor cell metabolism: ribosome biogenesis, glycolysis, glutaminolysis, fatty acid synthesis, nucleotide metabolism, lactate accumulation, and - possibly most suggestive of a stem-like phenotype - mitochondrial biogenesis [64, 65].