BRCA1 and breast carcinoma: A BRCA1-mutated breast cancer cell line transfected with wild-type BRCA1 has displayed the reversal of Warburg-like metabolic features, including an activation of OXPHOS and an impairment of glycolytic flux via the inhibition of the expression of genes that all play major roles in glycolysis (e.g. SLC2A1, HK1, HK2, PFKFB3, and LDHA) [94].