There were significant heterogeneities detected while evaluating the association between the LSP1 rs3817198 T > C polymorphism and breast cancer risk under all five genetic models (homozygous model: P = 0.032; heterozygous model: P < 0.001; recessive model: P < 0.001; dominant model: P < 0.001; comparison of allele frequencies: P < 0.001). Here, LSP1 is linked to breast carcinoma.