Pooled analysis indicated that there was a significant association between the LSP1 rs3817198 T > C polymorphism and increased breast cancer risk (homozygous model (CC vs. TT): odds ratio (OR) = 1.12, 95% confidence interval (CI) = 1.02–1.24, P = 0.021, Figure 2; as well as comparison of allele frequencies (C vs. T): OR = 1.09, 95% CI = 1.00–1.19, P = 0.039). The gene discussed is LSP1; the disease is breast cancer.