Patients with complete or partial remission following RFA or transarterial (chemo-)embolization according to mRECIST criteria, long tumor-free interval following successful resection or local ablative therapy, low alpha fetoprotein concentration and histologically proven lack of microvascular invasion, also have a good long-term prognosis and comparable risk for recurrence after LT despite an advanced tumor stage outside the Milan or within expanded criteria [20–22]. Here, AFP is linked to neoplasm.