In particular, we observed that luminal A breast cancers had the highest DRSs while basal breast cancers had the lowest DRSs (P = 5.7E-85, ANOVA) (Figure 2E), indicating that luminal A and basal breast carcinomas exhibit the lowest and highest PI3K-Akt-mTOR pathway activity, respectively. This evidence concerns the gene AKT1 and breast carcinoma.