Many of these studies have correlated increased TGFβ1 expression levels with advanced tumor stage and diminished patient survival, and elevated expression of TGFβ1 in these patients is associated with several specific aspects of tumor progression that include epithelial-mesenchymal transition (EMT), angiogenesis, tissue invasion and metastasis [35,36,37,38,39,40,41,42,43]. Here, TGFB1 is linked to neoplasm.