TGFB1 and neoplasm: In this light, a recent microarray analysis of gene expression in a TGFβ1-treated lung epithelial cell line versus a TGFβ1-treated lung adenocarcinoma cell line revealed differential regulation of gene expression by this cytokine in normal versus tumor cells, and the unique induction of several specific genes with tumor-promoting function by TGFβ1 in tumor cells was impaired by multiple MAPK pathway component inhibitors [62].