An example of this is Wnt5a, which has been shown to correlate with poor prognosis and promote tumor cell invasion in melanoma, glioma, pancreatic, prostate and gastric cancer [44,45,46,47,48,49], however in breast cancer, Wnt5a has been better characterized as a tumor suppressor [50,51,52]. The gene discussed is WNT5A; the disease is glioma.