Nocturnin null mice (Noc−/−) are resistant to diet‐induced obesity and hepatic steatosis, suggesting a key role for Nocturnin in liver metabolism.39Noc–/– mice have disrupted lipid processing in the gut and liver, likely due to altered polyadenylation of several key processing enzymes.40 Thus, posttranscriptional control of mRNA, including for enzymes involved in liver metabolism, is regulated by the molecular clock. Here, NOCT is linked to fatty liver disease.