FOXO1 and neoplasm: An examination of our comparative transcriptomic analysis revealed that of the 846 differentially expressed mRNA, 93 (nearly 11%) have biological functions important for cellular proliferation (Table 1), twelve of which have previously described PAX3-FOXO1 binding sites in their proximal promoter (Table 1, carat) [29], and 30 had altered gene expression levels consistent with changes seen in human tumor samples [30–33] (Table 1, pound sign).