PNPLA2 and prostate carcinoma: It is noteworthy that the expression of tumor-derived monoacyl glycerol lipase (MAGL), a lipase previously implicated in prostate cancer progression [62, 63], was also induced in response to adipocytes and persisted upon inhibition of adipocyte ATGL with Atglistatin, suggesting an additional possible compensatory mechanism in tumor cells that might be contributing to the adipocyte-driven metabolic phenotype (Supplementary Figure 10A).