We collected whole fallopian tubes from 11 patients (BRCA1/2 mutation positive or with a family history of breast or ovarian cancer) who underwent RRSO and performed extensive sectioning (∼3000 slides) to detect SOC precursor lesions under the supervision of a pathologist (L.R.)(Figure 1A-1E and Table 1). This evidence concerns the gene BRCA1 and ovarian carcinoma.