NKAIN2 and Global developmental delay: Chromosomal translocations at NKAIN2 gene were observed in the European population, including translocations t(1;6)(q32.3;q22.3) and t(2;6)(q24.3;q22.31), which resulted in constitutional inactivation of NKAIN2, but they were detected in patients with developmental delay [17] and neurological disorders [18] rather than with malignancy.