UBE2C and esophageal squamous cell carcinoma: The expression of UBE2C was able to accurately discriminate ESCC samples from normal (p<0.0001) and tumor surrounding tissues (p<0.0001), with sensitivity and specificity of, respectively, 88.46% and 100% (discrimination between ESCC and healthy esophageal tissue) and 71.15% and 73.08% (discrimination between ESCC and normal surrounding tissue) (Figure 3).