We also detected significant associations between the XPG rs2296147T>C polymorphism and PFS of CRC patients (TT vs. CC, HR = 1.74, 95% CI, 1.08-2.82, P = 0.023, Figure 3B; CT vs. CC, HR = 1.78, 95% CI, 1.09-2.90, P = 0.021; TT+CT vs. CC, HR = 1.32, 95% CI, 1.05-1.67, P = 0.019, Table 3). The gene discussed is ERCC5; the disease is colorectal carcinoma.