Moreover, homozygous deletion of p18 is frequently detected in B cell lymphomas [25, 26] and its deletion in mice promotes the development of various tumors, including medulloblastoma, glioblastoma, tumors of neuroendocrine organs, lungs, mammary and prostate [20, 27–32]. This evidence concerns the gene CDKN2C and B-cell non-Hodgkin lymphoma.