Earlier studies investigated the expression of MMPs in primary human breast cancer and breast cancer cell lines, concluding an enhanced expression and secretion of MMP1, -2, -3 (only in cell lines), -7 (with restriction), -10, -11, -12, -13, -14, -23, -27 and -28 in highly metastatic cell lines [4, 5]. This evidence concerns the gene MMP1 and breast carcinoma.