In previous studies, we showed that cerebral hypoxia and cerebral ischemia induce a strong angiogenic response in the brain, which correlates with induction of fibronectin and its two receptors, α5β1 and αVβ3 integrins on angiogenic cerebral vessels [5, 6, 9, 48, 49]. Here, FN1 is linked to Cerebral ischemia.