We used Spearman correlation analysis to confirm this result, and found high GRAMD1A levels was significantly correlated with pathologic differentiation (rs = 0.210, p = 0.040) and Survival or Mortality (rs = 0.329, p = 0.001), suggesting GRAMD1A was associated with HCC progression. This evidence concerns the gene GRAMD1A and hepatocellular carcinoma.