In rodent models of pancreatic cancer, vesicles similar to exosomes can carry and transport tumour-specific biomarkers into the saliva.36 It was found that KRAS, MBD3L2, ACRV1 and DPM1 levels enabled the differentiation of patients with pancreatitis and healthy individuals.37 It was also found that hsa-miR-210 and let-7c were overexpressed in the saliva of patients with pancreatitis. The gene discussed is ACRV1; the disease is familial pancreatic carcinoma.