Complex phenotype comprised of limb-girdle muscular dystrophy (LGMD) with atrial fibrillation and tachy-brady syndrome, features of FPLD, short stature and facial dysmorphy was described by Mercuri in a patient with mutation p.E358K in exon 6 of the LMNA gene. The gene discussed is LMNA; the disease is familial partial lipodystrophy.