In conclusion, our study revealed that an EBV miRNA, EBV-miR-BART6-3p, could inhibit invasion and migration of EBV-associated cancer cells and change stress fiber integrity, through inhibition of its target LOC553103 expression, leading to the regulation of many EMT-related molecules, such as upregulated expression of E-cadherin, as well as downregulated β-catenin, Snail, and N-cadherin and metastasis markers and invasion-related genes, including MMP2 and MMP9 (Figure 8). This evidence concerns the gene SNAI1 and cancer.