RBM24 and cancer: RBM24, an RNA-binding protein (RBP) with a single conserved RNA recognition motif (RRM) domain, has been found to be preferentially expressed in cardiac and skeletal muscle tissues25, 26 and to play important roles in myogenic differentiation and heart development.26, 27, 28, 29 Furthermore, recent studies have demonstrated that it may regulate the stability of p21 and p63 mRNA transcripts in different human cancer cell lines.30, 31 However, the exact functions of RBM24 in tumorigenesis and cancer progression are largely unknown.