RBM24 has been shown to alter the mRNA stabilities of p21 and p63 in different cancer cell lines.30, 31 Many recent studies have found that the dysregulation of miRNAs in NPC is related to disease prognosis and clinical outcome.16, 17, 18, 19 We compared the miRNA expression profiles of three Tet-Off-inducible RBM24-stable cell lines and found that miR-25 was the most significantly upregulated miRNA in RBM24-induced cells. The gene discussed is RBM24; the disease is cancer.