IL31RA and hemolytic-uremic syndrome: The analysis of the plasmid profiles substantiated the finding that the 3 HUS-associated strains carried the large virulence plasmid of VTEC, revealing the presence of a sequence 100% homologous to the replicon sequence of the pO26-CRL plasmid from a VTEC O26:H- (GenBank accession no. GQ259888.1), which harbors the genes ehxA, espP, and katP.