On the other hand, we found HRs of CHD among subjects with no minor allele for AGT rs2493137 (2.06; 95%CI: 1.48–2.87) and APOE rs449647 (1.70; 95%CI: 1.36–2.12); whereas, the toxic effects of lead tended to decrease among subjects with one or two minor alleles. The gene discussed is APOE; the disease is coronary artery disorder.