Because the Lund-Mackay CT score represents the severity of sinus inflammation, we believe that an increased expression of IL-10 in the tissues can also be an indicator of poor prognosis for medical and surgical treatment in patients with CRSwNP, though other inflammatory cytokines such as IFN-r, IL-5, IL-17A and IL-25 also correlate with the PNS CT score. This evidence concerns the gene IL25 and chronic rhinosinusitis with nasal polyps.