Even though some researchers noted the reduction of SBP1 is likely to occur in the later stages of tumor development in gastric carcinoma[24] and SBP1 levels were shown a trend toward a progressive loss with increasing tumor size in the case of uterine leiomyomas.[25] But we just observed that the change in SELENBP1 expression occurs in the stage of tumorigenesis and no further changes occur with the progress of the cancer. This evidence concerns the gene SELENBP1 and Uterine leiomyoma.