We further analyzed the relationship between SELENBP1 expression and recurrence or metastasis of NPC; the results show that low SELENBP1 expression was associated with high tumor recurrence and metastasis (Fig. 5B and C), indicating that negative SBP1 expression could be a potential biomarker predicting early recurrence or poor prognosis in NPC patients, so the internal mechanism is worth further research and exploration. Here, SELENBP1 is linked to neoplasm.