CCND2 and renal cell adenocarcinoma: As is shown in Table 1, the methylation of CCND2 was observed in 29/102 (28%) of RCC tumors, but only 2/23 (8.7%) in adjacent non-malignant tissues (Table 1), which suggested that CCND2 methylation was more likely to occur in tumor tissues, as is shown in Fig 4A.