To extrapolate the predicted detection rate for prelingual SNHL by this kit from our data, we counted the number of subjects with prelingual SNHL and also the number of subjects carrying any of the nine target variants of the GJB2, SLC26A4 and CDH23 genes selected for our U-TOPTM HL Genotyping Kit. This evidence concerns the gene CDH23 and sensorineural hearing loss disorder.