GAK and Parkinson disease: In addition to those five genes, two SNPs, rs1564282 and rs11248060, in the GAK (cyclin G associated kinase, a cell cycle regulator)/DGKQ (DGKθ) region were repeatedly reported to be associated with PD by Pankratz et al. (2009), and Simón-Sánchez et al. (2011) (Table 1).