To further identify the genetic variants in hypospadias, van der Zanden et al. performed the first GWAS using European samples of anterior or middle hypospadias patients and found that two SNPs, rs1934179 and rs7063116, in DGKκ, which mapped to Xp11.22 and encodes DGKκ, exhibited a significant association (van der Zanden et al., 2011; Table 1). The gene discussed is DGKK; the disease is hypospadias.