Forty-five pathways were constructed, including 16 pathways linked to the two miRNAs, among which PI3K-Akt signaling pathway (map04151), mTOR signaling pathway (map04150), regulation of actin cytoskeleton (map04810), axon guidance (map04360), MAPK signaling pathway (map04010), glioma (map05214), and gap junction (map04540), were associated with the pathogenic mechanism with neurodegenerative diseases. Here, AKT1 is linked to central nervous system cancer.