However, the 19q12 amplicon comprises several genes along with CCNE1, including URI (C19Orf2, RPB5-mediating protein), C19Orf12, POP4 and PLEKHF1. We and others recently observed URI amplification in carcinomas of the ovary [5–7] and endometrium [6]. Here, CCNE1 is linked to ovarian carcinoma.