The reason for the greater amount of liver fat in the Chinese as compared to Europids is probably due to the difference in the genes related to human body fat distribution, but it is unlikely to be the difference in the frequency of the known two most common gene variants causing NAFLD i.e. the I148M variant in PNPLA3 [27] and the E167K variant in TM6SF2 [28]. This evidence concerns the gene TM6SF2 and metabolic dysfunction-associated steatotic liver disease.