TERT and pancreatic neoplasm: At chr5p15.33, one of the four variants highly correlated with rs35226131 is a missense variant in the second exon of TERT (rs61748181: r2 = 1, D' = 1 in 1000G EUR) whereby the minor allele, associated with reduced risk of pancreatic cancer, changes amino acid 279 from alanine to threonine (A279T).