CD8A and neoplasm: Compared with normal hens, the mean frequency of CD8+ T cells was significantly greater (mean ± SEM = 18 ± 1.80 cells, P < 0.01) in the tumor stroma at early stage and increased further in the stroma of tumors at late stage OVCA (mean ± SEM = 26 ± 1.83 cells, P < 0.05) in 20,000 μm2 of the tissue (Figure 4(a)).