HEMK2 and non-small cell lung carcinoma: As for SEC61G and RPS7, they were both positively coexpressed with SEC61B in normal samples; in NSCLC samples, however, they were no longer positively coexpressed with SEC61B. The significant changes in the coexpression pattern of genes functionally associated with SEC61B in between normal and NSCLC cases indicated that it might be an important gene that could potentially have a large impact on NSCLC's development. N6AMT1 ranked the top among downregulated gene biomarkers.