Whether the infertility of Dgcr8 and Drosha germline cKO mice is caused by the loss of miRNA families in addition to miR-34 will be most efficiently answered by the generation of additional miR-family knockouts, with highly expressed miRNAs demonstrating unique germline expression patterns or those correlating with infertility being the most promising candidates. Here, DGCR8 is linked to Infertility.