Although both human endogenous and ectopically expressed mouse eIF4E3 proteins were able to bind the 7mG cap efficiently during cap-column chromatography, the interaction of ectopically expressed mouse eIF4E3 with eIF4G was not detected in mouse NIH 3T3 fibroblasts [20] but can apparently be observed in the HLY-1 diffuse large B-cell lymphoma cell line [29]. This evidence concerns the gene EIF4E3 and diffuse large B-cell lymphoma.