In the follow-up of 65 women of stage I-III HER2-positive cancer, there were lung metastases in 5, bone metastases in 4, liver metastases in 3, lung & bone metastases in 1, lung & liver metastases in 2, distant lymph nodes metastases in 1, and local recurrence without a distant metastasis in two women. Here, ERBB2 is linked to cancer.