S100B and infection: Neither magnitude nor breadth of Gag-, Pol- or Nef-specific responses were correlated with viral set point during the first year of infection (p > 0.05, Fig. 2a–f and Additional file 3: Figure S1a–S1f), although the magnitude of Nef at 1 year post infection was significantly positively correlated with viral set point (p = 0.01, r = 0.642, Fig. 2f).