To further test the hypothesis that there are associations between genetic variants of IL-17 and GCa risk, we genotyped the five most representative, potentially functional SNPs of rs1974226, rs2275913, rs3819024, rs4711998, and rs8193036 in the gene in a hospital-based case-control study in an eastern Chinese population of 1126 cases and 1221 cancer-free controls. The gene discussed is IL17A; the disease is cancer.