We examined the correlations between PD-1 and TIM-3 or TIGIT expression in CD4+ and CD8+ T cells in PBMC (n = 35, Figure 5A), AEM (n = 25, Figure 5B) and tumor tissues (n = 25, Figure 5C) from esophageal cancer patients. Here, HAVCR2 is linked to esophageal cancer.