TMSB4X and glomerulosclerosis: After 21 days, there was a range of abnormalities in Tmsb4x−/y and Tmsb4x+/y mice injected with NTS including collapse of capillary loops, segmental or global glomerulosclerosis, adhesion of the glomerular tuft to the Bowman capsule, and glomerular epithelial hyperplasia lesions, a feature of early crescent formation in this model.34