Furthermore, to investigate the pathophysiological role of intestinal urate excretion via ABCG2 in intestinal diseases, we also performed genotyping of ABCG2 dysfunctional variants in acute gastroenteritis patients whose ABCG2 function of intestinal urate excretion should be seriously impaired due to damage to the intestinal epithelium. This evidence concerns the gene ABCG2 and intestinal disorder.