CXCR4 and breast carcinoma: Another work [32] confirmed the central role of the same pathway in the chemotactic migration of BCCs towards bone-like cells, demonstrating how the protein Kisspeptin-10, known to inhibit metastasis of different cancer types, such as melanoma and breast cancer [33], negatively regulated the expression of CXCR-4 and consequently decreased MCF-7 migration towards MG63 bone cells.