Other important genes are reported to involve in immunological regulation of PD, included HLA, GBA (Glucosidase Beta Acid), SNCA (Synuclein alpha), LRRK2 (Leucine-rich repeat kinase 2) and NURR1 (Nuclear receptor related 1 protein) [33, 38]. The gene discussed is LRRK2; the disease is Parkinson disease.